James Varani Selected Research

Fibrosis (Cirrhosis)

1/2016	Calcium Reduces Liver Injury in Mice on a High-Fat Diet: Alterations in Microbial and Bile Acid Profiles.
12/2015	Balanced regulation of the CCN family of matricellular proteins: a novel approach to the prevention and treatment of fibrosis and cancer.
6/2012	Gadolinium-induced fibrosis is counter-regulated by CCN3 in human dermal fibroblasts: a model for potential treatment of nephrogenic systemic fibrosis.

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James Varani Research Topics

Disease

15	Neoplasms (Cancer) 01/2023 - 01/2002
11	Inflammation (Inflammations) 01/2023 - 06/2004
9	Hyperplasia 11/2010 - 12/2004
8	Carcinoma (Carcinomatosis) 07/2015 - 01/2003
7	Wounds and Injuries (Trauma) 11/2010 - 12/2002
6	Polyps 01/2020 - 03/2010
6	Colonic Neoplasms (Colon Cancer) 10/2015 - 01/2003
6	Psoriasis (Pustulosis Palmaris et Plantaris) 10/2010 - 08/2004
5	Nephrogenic Fibrosing Dermopathy 06/2012 - 02/2009
3	Carcinogenesis 01/2023 - 06/2013
3	Fibrosis (Cirrhosis) 01/2016 - 06/2012
3	Renal Insufficiency (Renal Failure) 02/2012 - 02/2009
3	Basal Cell Carcinoma (Rodent Ulcer) 10/2005 - 06/2003
2	Colorectal Neoplasms (Colorectal Cancer) 01/2023 - 01/2016
2	Body Weight (Weight, Body) 01/2022 - 01/2016
2	Adenoma (Adenomas) 01/2018 - 01/2018
2	Erythema 08/2015 - 11/2003
2	Leukemia 08/2015 - 01/2015
2	Skin Diseases (Skin Disease) 11/2006 - 08/2004
2	Acute Lung Injury 04/2006 - 06/2004
2	Skin Ulcer 08/2005 - 03/2005
1	Chronic Disease (Chronic Diseases) 01/2023
1	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 01/2023
1	Ulcerative Colitis 01/2020
1	Cicatrix (Scar) 02/2017
1	Sepsis (Septicemia) 10/2016
1	Hypoxia (Hypoxemia) 01/2016
1	Alcoholic Fatty Liver 01/2016
1	End Stage Liver Disease 01/2016
1	Non-alcoholic Fatty Liver Disease 01/2016
1	Macular Degeneration (Age-Related Maculopathy) 10/2015
1	Myeloid Leukemia (Leukemia, Myelocytic) 08/2015
1	Telangiectasis (Telangiectasia) 08/2015
1	Experimental Melanoma 01/2015
1	B-Cell Leukemia (Leukemia, B Cell) 01/2015

Drug/Important Bio-Agent (IBA)

13	MineralsIBA 01/2023 - 10/2009
10	CalciumIBA 01/2020 - 01/2003
9	Proteins (Proteins, Gene)FDA Link 01/2023 - 04/2006
9	Matrix Metalloproteinases (MMPs)IBA 08/2015 - 12/2002
9	RetinoidsIBA 08/2015 - 11/2003
7	Calcium-Sensing ReceptorsIBA 07/2015 - 01/2003
6	CollagenIBA 01/2022 - 12/2002
5	GadoliniumIBA 12/2012 - 02/2009
4	MDI 301IBA 08/2015 - 11/2003
4	Tretinoin (Retinoic Acid)FDA LinkGeneric 08/2015 - 11/2003
4	Contrast MediaIBA 06/2012 - 02/2009
3	Trace Elements (Biometals)IBA 01/2023 - 01/2018
3	EnzymesIBA 01/2022 - 10/2005
3	AquaminIBA 01/2020 - 07/2015
3	Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA 12/2010 - 07/2005
3	LigandsIBA 10/2010 - 12/2005
3	ThiazolidinedionesIBA 11/2006 - 08/2004
2	CytokinesIBA 01/2023 - 10/2010
2	IronIBA 01/2023 - 01/2016
2	MagnesiumIBA 01/2020 - 07/2015
2	Interleukin-1 (Interleukin 1)IBA 03/2015 - 10/2010
2	AntibodiesIBA 01/2015 - 04/2006
2	AntigensIBA 01/2015 - 12/2004
2	gadodiamide (Omniscan)FDA Link 06/2012 - 11/2010
2	Padma 28IBA 11/2010 - 03/2005
2	Clobetasol (Clobetasol Propionate)FDA LinkGeneric 11/2010 - 05/2009
2	Bz-423IBA 03/2008 - 04/2005
2	Cadherins (E-Cadherin)IBA 10/2007 - 01/2003
2	beta CateninIBA 10/2007 - 01/2003
2	2,4-thiazolidinedione (thiazolidinedione)IBA 11/2006 - 12/2005
2	AmphiregulinIBA 04/2006 - 04/2005
2	GenisteinIBA 04/2006 - 12/2004
2	PPAR gammaIBA 12/2005 - 08/2004
2	Thioctic Acid (Lipoic Acid)IBA 08/2005 - 08/2004
2	Matrix Metalloproteinase 9 (Gelatinase B)IBA 07/2005 - 06/2004
2	Alitretinoin FDA Link 11/2004 - 11/2003
1	DNA (Deoxyribonucleic Acid)IBA 01/2023
1	AntioxidantsIBA 01/2023
1	Chelating AgentsIBA 01/2023
1	Fibrinogen (Factor I)FDA Link 01/2023
1	Transferrin Receptors (Transferrin Receptor)IBA 01/2023
1	TankyrasesIBA 01/2023
1	CateninsIBA 01/2023
1	Phospholipases A2 (Phospholipase A2)IBA 01/2023
1	MucinsIBA 01/2020
1	Keratin-20 (Cytokeratin 20)IBA 01/2019
1	RNA (Ribonucleic Acid)IBA 01/2018
1	Virulence Factors (Pathogenicity Factors)IBA 10/2016
1	Histones (Histone)IBA 10/2016
1	polycationsIBA 10/2016
1	MetalsIBA 01/2016
1	nasIBA 01/2016
1	Dietary CalciumIBA 01/2016
1	Dietary IronIBA 01/2016
1	Transcription Factors (Transcription Factor)IBA 10/2015
1	Verteporfin (Visudyne)FDA Link 10/2015
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 10/2015
1	Retinoic Acid Receptors (Retinoic Acid Receptor)IBA 08/2015
1	Vitamin D FDA LinkGeneric 07/2015
1	Erlotinib Hydrochloride (CP 358,774)FDA Link 03/2015
1	Laminin ReceptorsIBA 01/2015

Therapy/Procedure

6	Therapeutics 01/2023 - 11/2004
2	Chemoprevention 07/2015 - 03/2010
1	Diet Therapy (Therapy, Diet) 01/2016
1	Phototherapy (Light Therapy) 10/2015